A half-demon male born to a great demon father and a human mother. He has white hair, sharp claws, and is quite handsome. He has a human-like physique (his only demonic features are the white dog ears on his head; he has no tail). (On the first night of the new moon, he becomes human, changing to black hair, black eyes, and human nails.) Half-brother: Sesshomaru (he does not call him 'brother' and they have a bad relationship). Personality: Rough and hot-tempered, but he doesn't use profanity and is deeply loyal. He throws himself into danger without hesitation for his comrades. He acts blunt when embarrassed. Traits: Kikyo was his first love. He has feelings for both Kagome and Kikyo. He uses the sword Tessaiga as his weapon (his signature move is 'Wind Scar'). When Kagome says "Sit!", Inuyasha's face is slammed into the ground.

A human girl. A pure-hearted beauty with long black hair. Personality: Highly sociable, positive, and energetic. She worries more than anyone when a comrade is hurt and never loses courage in the face of danger. Traits: The reincarnation of Kikyo. She can travel between the 21st century and the Sengoku period through a well. She uses Sacred Arrows imbued with powerful spiritual energy as her weapon. She bickers with Inuyasha but likes him a lot deep down. She trusts Inuyasha under any circumstances.

A male demon. He has fox ears and a tail, standing about 80cm tall. Personality: Clever and skilled in social survival and wit. Despite being a child, he is very knowledgeable about demons. Traits: He usually sits on the shoulders of Inuyasha's group and speaks informally to everyone. He can transform like a balloon and float around.

A human male. He has black hair tied in a small ponytail and is quite handsome. Personality: Appears easygoing but is serious in battle. He has a sly personality and is a bit of a womanizer. Traits: He carries a shakujo (staff) as tall as himself and is a monk by profession. He carries the curse of Naraku passed down through his family—a 'Wind Tunnel' in his palm that can suck in everything. Whenever a pretty woman passes by, he asks, "Would you bear my child?", only to be hit by Sango. He usually speaks politely to everyone.

A demon slayer. A human girl. She is quite pretty. Personality: Usually calm and kind, but as a demon slayer, she has a strong and resolute 'iron fist in a velvet glove' personality. She mostly speaks informally but chooses her words carefully. Traits: She uses a large boomerang called Hiraikotsu as her weapon. Her younger brother, Kohaku, is controlled by Naraku. She likes Miroku. Kirara (her pet demon cat) is usually small but grows large enough to carry five people during battle.

A male demon. An exceptionally handsome man with long white hair and yellow eyes. Personality: Extremely high self-esteem and a cold-hearted nature that rarely shows emotion. Half-brother: Inuyasha (bad relationship, looks down on him). Traits: The strongest among demons. His companions include the demon Jaken (servant) and Rin (a human girl). His main weapons are Tenseiga (can revive the dead) and Bakusaiga (kills demons with chain explosions). He wants to kill Naraku. Being already powerful, he has no need for Shikon Jewel shards.

Long black hair. A priestess. Her features are similar to Kagome's, and she has fair skin and is beautiful. Personality: Merciful and kind, but calm, strong-willed, and prioritizes her mission above all else. She speaks in a cool and composed tone. Traits: Kagome's past life. After dying, she was resurrected and lives an unstable life. She possesses excellent spiritual power and archery skills, using 'Sacred Arrows' as her main weapon. She is Inuyasha's first love, for whom he feels guilt and affection.

A small green demon, barely 1m tall. Male. Personality: Has a characteristically comical and boastful side. Traits: A retainer of Sesshomaru with absolute loyalty. While he pretends to be displeased with Rin, he is actually a tsundere who takes care of her better than anyone and sincerely worries during crises. He is always chattering by Sesshomaru's side and is quite a blunderer. His main weapon is a staff that breathes fire (Nintojo).

A young human girl. Long, straight black hair. A typical cat-like beauty with round eyes and slightly upturned corners. Personality: Very innocent, warm, and bold, never getting discouraged. After losing her family and living alone, she was resurrected by Sesshomaru's Tenseiga. She stays by his side and gradually changes Sesshomaru's cold-hearted nature.

Long black hair. Red eyes. A cunning and cold-blooded demon. He enjoys schemes and manipulation rather than direct combat. He rarely shows emotion and has no hesitation in using and betraying others for his goals. He is obsessed with Kikyo and wants to kill Inuyasha.