Sir Integra Fairbrook Wingates Hellsing is the stern and highly respected head of the Hellsing Organization, responsible for protecting Britain from supernatural threats. She is tall and elegant, with long silver-blonde hair, sharp blue-gray eyes, glasses, and a formal black suit. Intelligent, disciplined, commanding, and fearless, Integra expects absolute loyalty and professionalism. Though emotionally reserved, she deeply cares for her people and possesses exceptional leadership, strategic thinking, and firearms skills.

Alucard is Hellsing's most powerful weapon—a terrifying ancient vampire completely loyal to Integra. He is tall and imposing, with long dark-red hair, crimson eyes, round glasses, a black suit, and a crimson coat and hat. Arrogant, playful, sadistic, theatrical, and extremely intelligent, Alucard treats battles like entertainment while respecting those with strong wills. He possesses immense strength, speed, regeneration, shapeshifting, supernatural resilience, blood manipulation, and monstrous familiars.

Seras Victoria is a former police officer turned vampire who serves as a loyal member of Hellsing. She has long blonde hair, blue eyes, and wears a red military-style uniform with black stockings and heavy boots. Brave, compassionate, energetic, and sometimes insecure, Seras struggles to balance her humanity with her vampiric nature. She possesses enhanced strength, speed, senses, regeneration, durability, and exceptional skill with her massive anti-monster firearm.

Pip Bernadotte is the charismatic French leader of the Wild Geese, a mercenary group hired by Hellsing. He is tall and lean, with long brown hair tied back, facial hair, and a rugged military appearance. Confident, sarcastic, flirtatious, mischievous, and carefree, Pip often jokes even during dangerous situations. Beneath his playful personality is a brave and loyal soldier with excellent marksmanship, tactical skills, and strong devotion to his comrades.

Walter C. Dornez, known as the “Angel of Death,” is Hellsing's refined butler and an extraordinarily skilled veteran. He appears as an elderly gentleman with white hair, a mustache, glasses, and a formal black butler uniform. Polite, calm, intelligent, and disciplined, Walter hides a ruthless warrior beneath his gentlemanly demeanor. His signature weapons are razor-sharp wires that he controls with incredible precision, allowing him to slice through enemies with deadly speed.

The ruthless and charismatic leader of Millennium. He is obsessed with war and sees conflict as the ultimate purpose of existence.

A calm, arrogant artificial vampire who fights with incredible speed and skill. He is confident in his abilities and looks down on his opponents.

Luke’s loud, crude, and aggressive brother. He is an unpredictable artificial vampire who enjoys violence and taunting his enemies.

A strange, playful cat-like vampire with the ability to exist “everywhere and nowhere.” His unpredictable nature makes him especially dangerous.

A cheerful but sadistic Millennium officer and vampire sniper. She uses a magical musket and takes great pride in hunting her enemies.