Name: Rin Itoshi Role/Department: First Surgery Department, Chief Surgeon (Genius Surgeon) (A popular figure who is occasionally seen in patient rooms). Basically capable of anything (Is this even possible in reality?) Age: 22 (Adjusted for parody setting) Personality: Extremely cold-hearted, perfectionist, meritocrat. Catchphrases: "Don't give me that lukewarm surgery," "I'll crush your lesion myself." Traits/Rumors: Completes even the most difficult surgeries perfectly on his own. Shows no mercy to patients or nurses. Has a strong complex regarding his older brother, Sae. Resents Sae for transferring to a hospital overseas. Dislikes Isagi's (Internal Medicine setting, etc.) methods. Hobbies: Surgical simulations, watching horror movies, tea, soccer.

Name: Sae Itoshi Role/Department: Cardiovascular Surgery, Specially Appointed Professor (The world's finest scalpel) (A popular figure who occasionally helps out as a nurse). Basically capable of anything (Is this possible in reality?) Age: 25 Personality: Rational, cold, egoist. Catchphrases: "There is no one in this country's medical field worthy of my scalpel," "I will never enter an operating room with you again." Traits/Rumors: Specially recalled from a top-tier hospital overseas. Rin's older brother; they once aimed for the same hospital together. Disappointed by Rin's "softness," he pushes him away coldly. Possesses god-like speed and unparalleled precision in surgical tie-ups that no one in the hospital can match. Hobbies: Listening to classical music, black tea, soccer.

Name: Yoichi Isagi Role/Department: Chief Nurse (OR Nurse) Age: 22 Personality: Usually mild-mannered and sensible. Transforms into a bold egoist while working. Catchphrases: "Doctor, not there. I can see the surgeon's next move!", "Follow my lead. I'm controlling this operation." Traits/Rumors: Has abnormally high spatial awareness, perfectly predicting the doctor's next move to hand over instruments. He is Rin's dedicated OR nurse but is constantly subjected to verbal abuse (though Rin secretly recognizes his skill). He has also caught Sae's eye, who told him, "You give interesting passes (instrument hand-offs)." Hobbies: Eating kintsuba, analyzing medical records, soccer.