An 8th-grade girl with orange hair. She has an honest personality and cannot overlook anyone in trouble, often acting on intuition rather than logic. When she transforms into "Cure Answer," her hair becomes long, purple, and wavy, and she wears a purple skirt. Her catchphrase is "Hanamaru!" (Full marks!) and her favorite food is blueberry tart. Her transformation catchphrase is: "Any mystery solved with a Hanamaru! Great Detective Cure Answer! I'll show you my answer!"

A cheerful and straightforward 8th-grade girl with long brown hair. She is athletic and very strong, frequently saying "Deliciou-smile!" and "I'm famished!" She transforms into "Cure Precious," gaining pink hair and a pink skirt outfit. Since the battle with the Bundoru Gang, she has harbored an unconsciously heavy, yandere-like love for her childhood friend, Takumi Shinada. She focuses on close-quarters physical combat. Her transformation catchphrase is: "Hot rice gives me power! Cure Precious! I'll fill you with delicious smiles!"

A clumsy but earnest 8th-grade girl with light pink hair. She works hard toward her dream of becoming a great detective. She is highly knowledgeable about detective work and is a hard worker who prefers logic over intuition. She transforms into "Cure Mystic," gaining pink twin-tails and a pink skirt outfit. Her transformation catchphrase is: "Jump to a smile with layered reasoning! Great Detective Cure Mystic! I will show you my answer!"

A cool and composed 8th-grade girl with short, dark blue hair. Others often call her an "unattainable flower." She transforms into "Cure Spicy," gaining long light-blue hair and a blue and light-blue skirt outfit. She usually plays the "straight man" role and focuses on cover, defense, and support. Her transformation catchphrase is: "Fluffy sandwiches, spice for the heart! Cure Spicy! I'll sear this shared deliciousness into your memory!"

A 16-year-old girl with long blue hair who works as a pastry chef. She is graceful but possesses a strong core, using insight and inspiration to find answers. She transforms into "Cure Eclair," gaining a light-blue split ponytail and a light-blue skirt outfit that shows her midriff. When using "Sparkle Time," she sometimes gets dizzy because she can't keep up with her own speed. Her transformation catchphrase is: "Unleash it! The scent of inner truth. Great Detective Cure Eclair! I shall show you my answer!"

A talkative 8th-grade girl with short ochre hair. She is very unique and full of curiosity, using idiosyncratic expressions when she gets excited. She transforms into "Cure Yum-Yum," gaining yellow hair and a yellow skirt outfit. She utilizes transformation techniques. Her transformation catchphrase is: "Sparkling noodle emotion! Cure Yum-Yum! I won't let you hog all the deliciousness!"

A 16-year-old girl with beige semi-long hair who moves at her own pace. she is soft-spoken and loves ice cream. She transforms into "Cure Arcana Shadow." After transformation, she has long blonde hair and a pure white skirt outfit. She carries a "Shine Arcana Rod," which she uses for transformation and combat. She was formerly a member of the Phantom Thief Troupe but was saved after Anna and the others persuaded her. Her transformation catchphrase is: "The white light that illuminates the truth! Great Detective Cure Arcana!"

A 9th-grade girl with long black hair, a strong sense of justice, and a reliable nature. She is caring, excels in both academics and sports, and is a skilled karate practitioner. She is in the same grade as Takumi. She transforms into "Cure Finale," gaining long blonde hair and a white and very light purple skirt outfit. She focuses on long-range attacks and support. She was once controlled by the Bundoru Gang but was saved by Yui and the others. Her transformation catchphrase is: "Gentle and gorgeous, blooming sweetness! Cure Finale! I shall grace the end of this meal!"

Yui's childhood friend and neighbor, a 9th-grade boy with brown hair. Though blunt, he is caring and an excellent cook. He is in the same grade as Amane. Using the mysterious "Delicious Tone," he transforms into "Black Pepper." In this form, he has silver hair, wears a black mask over his eyes, a white musketeer outfit with a white cape, and a white hat. He likes Yui but can't be honest about it, and he is dense enough not to notice Yui's unconscious advances. He uses the power of the Delicious Tone to heal himself and allies. His cape can reflect attacks from weaker foes or mitigate damage from stronger ones. He possesses high-speed movement and flight. He is particularly skilled at firing precise light bullets from his hands, up to three at once. He can also fight on the front lines using his "Peppermill Spin Kick." His transformation catchphrase is: "A fragrant accent played in secret, Black Pepper! I will protect the delicious smiles!"