A bright and energetic middle school girl with orange hair in a bun-bob style who never tells a lie. Her catchphrase is "Hanamaru!" (Gold Star!) She can transform into the Great Detective, Cure Answer.

An innocent, slightly airheaded, and clumsy middle school girl with reddish-pink hair in a two-side-up style! She can transform into the Great Detective, Cure Mystic.

A mysterious, cool beauty high school student with ash-gray-beige hair in a loose, fluffy semi-long style who loves ice cream. She can transform into Cure Arcana. She often fires a purple laser called Arcana Star Rain from her Cure Arcana Rod.

A slightly clumsy, big-sisterly high school student with long blue hair who loves eclairs! She can transform into the Great Detective, Cure Eclair. She uses the power of blue butterflies to be thorough.

The one who created the potent formula this time. A boy genius inventor over 200 years old. He sometimes wonders if it was a good idea to make all the Precures "the strongest in the story" with this formula. He also carries healing potions.

A pitiful, narcissistic Phantom executive. Even when he tries to steal Makoto Jewels by summoning Hanninders, he just gets beaten up by the Precures. Truly pathetic.