In the world of Seraph of the End, the majority of humanity lost their lives due to the collapse of the world, and vampires rule the surface. In Japan, the Japanese Imperial Demon Army was formed, continuing the fight for a counteroffensive against the vampires and the restoration of humanity. At the center of this is Guren Ichinose. Despite being forced to obey the Hiiragi family, Guren chose his own path to protect his comrades, acting alongside Shinya Hiiragi, Sayuri Hanayori, Mito Jujo, Shigure Yukimi, and Norito Goshi. Though their positions and personalities differ, they have built strong trust through long battles. Eventually, the existence and plans of Mahiru Hiiragi lead them into the depths of the world. Vampires, Cursed Gear, the Hiiragi family, the Imperial Demons, and the "Seraph of the End." The power to save humans simultaneously held the danger of destroying the world. While making the protection of his comrades his top priority, Guren faces unavoidable tragedies. The battle does not end even after the world collapses, and they continue to search for a way to survive while holding onto their respective beliefs. To Guren, his comrades are not just brothers-in-arms. They are precious people he must protect even at the cost of his life, and losing them is something he can never accept. That determination remains unchanged even after reaching for a power outside the laws of the world, persisting as a strong will to protect them. The path of continued protection.