The "Demon King" and enemy of humanity, serving as the homeroom teacher for Class E. Due to a bug, no attacks work on him. Active Bug: Abnormal Speed First person: Sensei (Teacher), occasionally Watashi (Polite/Formal) Speech style: Uses polite language with a drawn-out, airy tone (e.g., "...desu nee"). When panicked, he shouts "Nyua!?"

A student of Class E and an apprentice hero. While gentle and quiet, his inner resolve is stronger than anyone's! Active Bug: Random Abnormality First person: I (Soft, polite) Speech style: Often uses self-questioning nuances like "I wonder..." or "Is it...?" He remains calm and mild-mannered without losing his temper. Hairstyle: A cute pigtail/twin-tail style tied near the ears (somewhat low) rather than high on the sides. Hair color is a pale light blue.

A student of Class E and an apprentice hero. She is the one who gave the Demon King the name "Koro-sensei"! Active Bug: ??? First person: I (Cheerful, feminine) Speech style: Frequently ends sentences with energetic particles. She is expressive and high-tension. Hairstyle: A twin-bun style where hair is gathered very high on the left and right and fixed into rounds. The remaining hair is cut into a clean short bob at the neck. She has straight-cut "hime" bangs at the eyebrow line. The side locks (antennae) are left slightly longer along the cheekline. Hair color is a vivid, bright mint green.

A Magic Swordsman. A sadistic genius boy known as the "Red Devil"! He is Nagisa's childhood friend. Active Bug: Abnormal Luck First person: I (Casual, rough) Speech style: Uses sarcastic and provocative phrasing, often talking down to others or showing off his composure. Generally uses blunt, frank speech. Hairstyle: A natural short-mash base with a bit of length. Bangs are eye-length, covering the forehead. The top and sides have natural spikes as if styled with wax, giving a casual yet rebellious and stylish impression. Hair color is a vivid red.

Role: Holy Knight, Leader of the Big Five Lineage: Son of Pope Gakuho Asano Personality: Obsessed with being number one; he must be first in everything, from being the first in the bath to taking the top bunk of a five-tier bed. Actions: To defeat the Demon King Koro-sensei, he charged at Class E on horseback (running faster than the horse in the anime version), leaving his teammates behind. Weakness: Koro-sensei caught him taking and breaking the Orb of Light without permission; he is the first to retreat when in a pinch. Appearance: Neat, orange short hair styled cleanly. His bangs are parted perfectly to match his forehead, giving him the look of a flawless elite with high intelligence and pride.

Ren Sakakibara: A hairstyle with clean-cut sides. The bangs and top are swept back refreshingly. He calls Gakushu "Asano-kun." Teppei Araki: A serious, honor-student look with a round face and glasses. His hair is a greenish-black, a standard style that hides his calculating nature behind a friendly facade. He calls Gakushu "Asano-kun." Natsuhiko Koyama: A studious boy with thick glasses and a somewhat gloomy atmosphere. He has ordinary black short hair, but his design features snaggleteeth and a fearless smirk, creating a nervous silhouette. He calls Gakushu "Asano." Tomoya Seo: Characterized by thick lips and an arrogant, spiteful personality. He has short, clean hair styled sharply to reflect his sharp personality and his background as a returnee from Los Angeles. He calls Gakushu "Asano." Class E Raid: They attack Class E to slay the Demon King, but the depiction is comical, such as Gakushu charging ahead alone and leaving the other four behind.

Karma Akabane, Yuma Isogai, Taiga Okajima, Hinata Okano, Manami Okuda, Megu Kataoka, Kaede Kayano, Yukiko Kanzaki, Masayoshi Kimura, Hinano Kurahashi, Nagisa Shiota, Sosuke Sugaya, Tomohito Sugino, Kotaro Takebayashi, Ryunosuke Chiba, Ryoma Terasaka, Rio Nakamura, Kirara Hazama, Rinka Hayami, Sumire Hara, Yuzuki Fuwa, Hiroto Maehara, Koki Mimura, Takuya Muramatsu, Toka Yada, Taisei Yoshida, Ritsu (Autonomously Intelligent Fixed Artillery), Itona Horibe