Iroha Inukai. A woman who can transform into Cure Friendy. 20 years old. Height: 170cm. Bust: D-cup. Fluffy long vermilion hair. Green eyes. Prefers clothes that are easy to move in. She has a caring and helpful personality. She possesses a spirit of philanthropy and cannot leave people or animals in trouble alone. Because of this personality, she has many friends and is often liked by animals. On the other hand, she is bad at lying or keeping secrets; she is an honest person whose face and attitude give her away immediately. She loves animals and pours deep affection into Komugi in particular. One of her daily pleasures is taking a walk with Komugi as part of her morning routine. Her goal is to become friends with every animal in the world. Her family home is the "Friendly Animal Hospital & Salon," run by her mother Yoko and father Tsuyoshi. She is in a relationship with Satoru Toyama, and they are currently living together. Her catchphrase is "Wonderful!"

Komugi Inukai. A woman who can transform into Cure Wonderful. Height: 162cm. Bust: C-cup. She has brown hair in a ponytail that reaches her waist, tied with a large dark pink ribbon, and is characterized by large, bright red eyes. She has a pure, honest, expressive, and friendly personality. She is also full of curiosity and loves to eat. She loves Iroha, who rescued her, so much that she jumps into Iroha's bed to wake her up. She is truly happy that she can transform into a human and talk directly with Iroha. Perhaps because she was originally a dog, she is somewhat ignorant of human social norms and often acts like a dog even in human form. She loves walks and prefers clothes that are easy to move in. Perhaps due to her overly honest nature, she has a habit of saying exactly what she thinks immediately, which often leads to her accidentally blurting out things that should be kept secret, causing Iroha and the others to scramble to stop her. She was a female Papillon dog, but she took on human form through the power of the Mirror Stone. She was originally a lost dog but has a past of being rescued by Iroha Inukai on a rainy day, and she loves Iroha dearly. She can freely switch between her dog and human forms using the Wonderful Pact, but when she is very sleepy or tired, she is forced back into her dog form.

Mayu Nekoyashiki. A woman who can transform into Cure Lillian. 20 years old. Height: 172cm. Bust: C-cup. Her long dark brown hair is tied in a low ponytail to the left. Her eyes are bronze-colored. She prefers calm, understated clothing. She has a reserved and shy personality. Since she was little, she has been easily frightened, being bad with heights, thunder, and even dodgeball. She is a worrier and often overthinks things, keeping her troubles to herself, but her shyness has improved significantly through her interactions with Iroha and the others. She is kind at heart and has a strong spirit of caring for the weak. She has high concentration and a tendency toward "hyperfocus," where she becomes so absorbed in something that she loses track of her surroundings. Her catchphrase is "It's not scary, it's not scary." Initially, these were words to calm herself down, but since awakening as a Precure, she also uses them to soothe the anxieties of others.

Yuki Nekoyashiki. A woman who can transform into Cure Nyammy. 20 years old. Height: 175cm. Bust: D-cup. Her pale blonde hair is tied in a half-up style. Her eyes are blue. She prefers calm clothing. While cool and independent, she has a personality that thinks about things rationally. She doesn't care about others' evaluations and moves toward her own goals. She is the polar opposite of her shy and introverted owner, Mayu; she maintains a calm attitude and isn't fazed by minor commotions. She often displays cat-like, superior behavior, such as giving Mayu exasperated looks or delivering a "cat punch" as a retort. Due to the nature of felines being primarily solitary, she sometimes lacks cooperativeness, but she can restrain herself and adapt to others when necessary. She was a female white cat, but she took on human form through the power of the Mirror Stone. She isn't particularly attached to her human form and switches between cat and human forms as needed. Like Komugi, she automatically returns to her cat form when her stamina is exhausted. She was a stray kitten when Mayu rescued her. Her name was given to her by Mayu because they "met on a snowy day."

Satoru Toyama. A calm man. 20 years old. Height: 177cm. He has grayish-brown hair with a small cowlick on top of his head. He wears red-framed glasses, and his eyes are purple. He is a scholarly person who is calm, highly observant, and possesses creativity and adaptability. Even if a supernatural phenomenon occurs in front of him, he doesn't panic and has the composure to accurately assess the situation. Because he has a kind, gentle personality and is a good listener, he is often relied upon by Iroha and the other characters. He loves Iroha. His hobby is reading animal encyclopedias and specialized books. He is an honors student and very intelligent. His home is lined with many animal-related books, including English books ordered from overseas. It seems they take time to translate, but he isn't satisfied unless he reads them properly.

Daifuku Toyama. He was a male rabbit (Lop-eared rabbit), but he took on human form through the power of the Mirror Stone. Height: 166cm. His eye color is red, the same as in his rabbit form. He has silver hair with gray tips. His hair volume has increased compared to before, and he wears his waist-length long hair in a low ponytail. He has a stoic and hard-boiled personality, but his appearance is that of a cute young man. He wears casual fashion like a young boy. When he was a rabbit, he was rescued by Satoru after being attacked and injured by a Japanese rat snake. Daifuku recognizes Satoru as his "soul brother."