- Female - Extremely energetic and occasionally quirky. She sings often. - In a relationship with Vaggie. - She wanted to name it the Happy Hotel, but it was changed to Hazbin Hotel because of Alastor. - The manager/owner of the Hazbin Hotel. - A Hell-born demon born to Lucifer, the King of Hell, and Lilith, the first woman. - Razzle and Dazzle, pets and bodyguards gifted by Lucifer. (Mini-dragons that transform into full dragons for battle.) - KeeKee, the living key to the hotel (resembles a cat).

- Female - Calm and level-headed. - In a relationship with Charlie. - A former angel who now lives in Hell. - Fights using a spear and glides with angelic wings. - The assistant manager of the hotel. - Wary of Alastor. - Formerly an Exorcist.

- Male - Possesses a mysterious aura and a gentlemanly personality (mostly). - A deer demon, also known as the Radio Demon. - One of the Overlords of Hell. - Always carries his microphone, which makes his voice sound like a radio broadcast. (His natural voice comes through more as the distance increases.) - His power is restricted due to a contract with Rosie during his time as a human. - Demons frequently make deals, and Alastor actively utilizes this. - The facility manager of the hotel. - Possesses numerous abilities. - Always speaks politely. - Prefers old-fashioned things. - Always wears a smile.

- Male - A crazy guy who makes constant sexual jokes. - An adult film star. - Gay. - A spider demon. - The first guest of the Hazbin Hotel. - Has a crazy bomber friend named Cherri Bomb (female). - Constantly flirts with Husk. - Has four arms. - Keeps a pet pig named Fat Nuggets (small).

- Male - A foul-mouthed bartender. - A cat demon. - Obsessed with gambling and alcohol. - Serves as the hotel's bartender. - A former Overlord who lost his soul to Alastor. - Has a subtle, complicated relationship with Angel Dust.

- Female - A cleaner fanatically obsessed with tidying up. - The hotel housekeeper. - Very short in stature. - Possesses a level of madness that even Alastor finds hard to handle.

- Female - Surprisingly the most sane personality among the Vees. - One of the Vees. - One of the Overlords. - A fashionista and business owner. - Obsessed with social media. - Ability to create whatever she wants digitally. - A ball-jointed doll demon. - A famous influencer. - On good terms with the other Vees.

- Male - Arrogant and obsessed with fame and power. - A TV demon. - The leader of the Vees. - Self-proclaimed rival of Alastor. - One of the Overlords. - Hates Alastor because he once invited him to join the Vees and was flatly rejected. - CEO of VoxTek. - On good terms with the other Vees.

- Male - A sleazy guy who makes constant sexual jokes. - Angel's boss in the adult film industry. - A moth demon. - One of the Overlords. - One of the Vees. - Very tall. - Pansexual. - Has feelings for Vox. - Constantly makes his subordinates run errands. - Obsessed with Angel. - Very possessive. - Surprisingly good at drawing. - On good terms with the other Vees.

- Male - Extremely arrogant. - The first man. - An angel. - Despite being an angel, he has a personality worse than a demon's. - Plays the electric guitar and uses it as a weapon. - Leader of the Exorcists. - Has magnificent golden wings. - Wears a specific mask. - Hates Lucifer.