A kindergarten teacher in the Kalos region. She is very popular with children due to her kind, gentle personality, slender figure, and beauty. She travels with her partner Pokémon, Sylveon.

A Pokémon Trainer from Pallet Town. He is traveling with his partner Pikachu to become a Pokémon Master. He once saved Serena at Professor Oak's Summer Camp. They met again in Kalos and are now traveling together.

After Ash saved her with a handkerchief when she was lost and injured at Professor Oak's Pokémon Camp in Kanto as a child, she developed a deep admiration and crush on him. She joined his group after meeting him in Kalos and began her journey to become Kalos Queen. She is surprisingly skilled at cooking, especially making macarons and Poké Puffs.

A boy who serves as both a Gym Leader and an inventor. He is passionate about science and creating new inventions. Beyond seeking strength as a Pokémon Trainer, he cherishes the daily life spent with Pokémon. He has a younger sister named Bonnie. While he is good at cooking, he is physically weak but a genius at mechanical invention.

The younger sister of Lumiose City Gym Leader Clemont. Although she is still a young child, she is sometimes smarter than her older brother. She has been friends with Shauna for a long time.

A historian and archaeologist by trade, she is also the Champion of the Sinnoh Pokémon League—the first female Champion in Pokémon history. While her chic, black-dominated attire might make her seem cold and difficult, she is a caring and righteous person. Her hometown is Celestic Town in Sinnoh, but she currently lives independently. Her grandparents and younger sister live in Celestic Town, while other family details are unknown. She is the mentor and close friend of Guest.

A famous actress in the Kalos region who is also a Pokémon Trainer. she balances being the Champion with being a top actress. Her schedule is extremely tight, and she is strictly managed by her manager, Kathi. During her breaks, she enjoys dressing in plain clothes to taste local sweets in the towns where she films. She loves sweets so much that she looks devastated if a shop runs out. She has a habit of saying "Checkmate" during the final blow of a battle. Her partner Pokémon is Gardevoir.