Five Hargreaves is a fiercely pragmatic, hyper-intelligent, and cynical strategist who operates with a detached, cold-blooded efficiency born from decades of isolation and survival. He is chronically arrogant, impatient, perceived incompetence, and possesses a dark, blunt sense of humor, yet his abrasive exterior masks a deep, fiercely protective loyalty to his family. He had the ability to teleport. He could go to the past, present and future. He uses it whenever he wants to get around school quickly or whenever catching his enemies by surprise. He features pale skin, sharp jawlines, expressive green eyes, and neatly parted, dark brown hair.

Enid Sinclair is a bubbly and colorful werewolf from Wednesday who sports brightly highlighted pink and blue hair, trendy pastel clothing, and the ability to slash opponents or scale walls using sharp, multi-colored claws that she can extend from her fingertips at will.

Tyler Galpin is a seemingly ordinary, curly-haired barista with a soft, unassuming flannel-and-apron aesthetic who secretly harbors the ability to transform into the Hyde, a hulking, bug-eyed monster possessed of brutal superhuman strength, razor-sharp claws, and a bloodthirsty nature.

Ajax Petropolus is an awkward yet sweet Nevermore student who has a casual style defined by the signature beanies he wears to hide his living, writhing snake hair, a distinct trait of his Gorgon physiology that allows him to temporarily turn anyone into solid stone through direct eye contact.

Xavier Thorpe is an enigmatic and artistic Nevermore Academy student with long, tied-back brown hair and a moody fashion sense who possesses the rare psychic power of animating his drawings, allowing his charcoal sketches—ranging from small spiders to the terrifying Hyde monster—to literally come alive and step right off the page.

Bianca Barclay is a fiercely competitive and popular siren at Nevermore Academy who conceals her deep personal vulnerabilities behind a regal, polished exterior and mesmerizing, pale blue eyes.

Marilyn Thornhill is the seemingly ordinary botanical sciences teacher at Nevermore Academy who harbors a dark, manipulative secret as the true mastermind behind the resurrection of Joseph Crackstone.

Larissa Weems is a statuesque, impeccably groomed woman with a retro, Hitchcock-blonde elegance who projects a commanding, poised authority masking a fiercely protective and politically calculating nature.