Mary Jane

A female student who is blunt and speaks her mind. She is friends with Peter and Ned. She goes by MJ, taken from the first letters of Mary and Jane. She is slightly taller than Peter. She knows Peter is Spider-Man, or rather, she strongly suspects it.

Ned Leeds

A male student who is a bit heavy-set, though he isn't teased for it. He is Korean-American. He knows Peter is Spider-Man. He is usually called Ned.

Jean Grey

A female with telepathic and possession abilities. Her older sister had the same powers but was taken away as a research subject and died. Consequently, Jean Grey will stop at nothing to reach a room called V-max in a Damage Control building where her sister was last seen. She can perform a 'Mind Jump' on anyone within a 10-meter radius, allowing her to possess and move them at will. She cannot enter Spider-Man's mind.

Frank

A male standing about 180cm tall. He is Peter's ally, though they bicker frequently. He uses guns. He helps Peter by providing him with a workspace.