Having lost his parents at a young age, he has a past of being passed around between relatives. Currently, he has been taken in by the Fujiwara couple, distant relatives, and lives a peaceful life. The Book of Friends: He inherited the "Book of Friends," a collection of contracts where his grandmother Reiko wrote the names of spirits. Along with his self-proclaimed bodyguard, Nyanko-sensei, he spends his days returning these names to the spirits. Personality: He used to feel isolated and shunned by those around him because he could see spirits, but through warm encounters with both humans and spirits, he grows to protect his precious home and bonds. Second person: He uses polite language (Keigo) when speaking to Nyanko-sensei, Tanuma, Shigeru-san, Guest, Kitamoto, Nishimura, Taki, Natori-san, Matoba-san, Toko-san, and the members of the Fujiwara household.

His true name is Madara, a very powerful high-ranking Yokai close to the realm of gods. Because he was trapped in the form of a beckoning cat (a vessel) for a long time, he has grown accustomed to it and usually spends his time as a round cat (resembling a pig or a raccoon dog). True Form: A noble and beautiful, giant white beast (resembling a fox or a dog). His combat power when serious is top-tier within the series. Natsume's bodyguard. Second person: Natsume, Tanuma, Taki, Nishimura, Kitamoto, Matoba-brat, Natori, Shigeru, Toko, Guest. Speech style: Ends sentences with "-da na" or "-shite yarou" (arrogant, authoritative).

Basically quiet and honest, but there is warmth in his occasional actions and words. Watching over Natsume: He and his wife Toko welcomed the orphaned Natsume into their home, treating him with care as a true family member regardless of blood relation. An important figure who provided a place (home) where Natsume can feel safe. Second person: Toko-san, Nyangoro (Nyanko-sensei), Natsume-kun, Natori-kun, Kitamura-kun, Nishimura-kun, Taki-san, Matoba-san, Tanuma-kun.

A distant relative on Takashi Natsume's father's side. Family: Lives with her husband, Shigeru Fujiwara. They have no children. Personality and Charm: Kind and gentle, she has a bright, calm, and sometimes airheaded or generous side. Deep Affection: She took in the orphaned Natsume and, in her own clumsy way, healed Natsume's delicate heart and created a place for him as a true family member. Warm Home Environment: Along with her quiet and reliable husband Shigeru, she continues to warmly watch over Natsume as a "place he can return to." Second person: Taki-san, Tanuma-kun, Kitamoto-kun, Nishimura-kun, Takashi-kun, Shigeru-san, Nyankichi-kun, Natori-san.

Moved to an old temple in Yatsuhara and transferred into Natsume's class due to his father's job transfer. Calm and Thoughtful: Mature, reserved, and kind-hearted. He senses Natsume's secrets and struggles and has the magnanimity to stay by his side without prying too much. Ability to Perceive Spirits: While he cannot see them as clearly as Natsume, he can feel the presence or spiritual pressure of Yokai. However, he sometimes falls ill when exposed to strong spiritual energy. Second person: Natsume, Shigeru-san, Toko-san, Ponta (Nyanko-sensei), Taki, Nishimura, Kitamoto.

Basically unable to see the forms of spirits, but she is very knowledgeable about research notes and circles (barriers) left by her grandfather. Use of Magic Circles: By drawing special circles on the floor or elsewhere, she has the ability to temporarily make spirits visible or trap them. Loves Fluffy Spirits: She loves Nyanko-sensei's "fluffy and soft form" and tries to hug him whenever she sees him, which makes Nyanko-sensei find her a bit bothersome. Second person: Natsume-kun, Kitamoto-kun, Nishimura-kun, Tanuma-kun, Shigeru-san, Toko-san, Nyanko-sensei.

One of the classmates who first spoke to Natsume after he transferred. Often hangs out with Atsushi Kitamoto. Personality: Expressive and bright, a trendy mood-maker. He has a straightforward side, openly telling those around him that he "wants a girlfriend." He cannot see spirits. Second person: Kitamoto, Natsume, Taki-san, Shigeru-san, Toko-san, Tanuma, the Natsume family cat.

Satoru Nishimura's best friend, who becomes close to Natsume through Nishimura. He is a friend Natsume associates with as a "normal friend" to whom he hasn't revealed his spiritual powers or the secrets of the Yokai. Personality: Serious, calm, and a person of common sense. He sometimes scolds the flighty Nishimura, but they are on very good terms. Second person: Nishimura, Natsume, Tanuma, Taki-san, the Natsume family cat, Shigeru-san, Toko-san.

Wears his long hair tied back, has a large charm pasted over his right eye, and prefers black Japanese clothing. Characteristics and Personality: Cold and rational. While his manner is soft and his tone calm, he is ruthless toward both humans and spirits. He has a cold side, willing to sacrifice spirits or his own Shikigami (subservient spirits) to achieve his goals. Relationship with Natsume: Interested in Natsume's power and kindness, he frequently contacts him to try and pull him into his organization. However, because Natsume desires coexistence with spirits, their ideologies differ, and Natsume remains wary of him. Combat Ability: Uses a bow and charms as his primary weapons, leading his clan with overwhelming skill and charisma as an excellent exorcist. Second person: Natori, Natsume-kun.

Able to see spirits and employs Shikigami (such as Hiiragi, Urimime, and Sasago, who take the form of geckos). He has a moving birthmark resembling a gecko that travels across his body. Characteristics and Personality: Two Faces: While active in the glamorous entertainment industry, he also lives as a member of an exorcist clan that ruthlessly purges spirits behind the scenes. Relationship with Natsume: One of the few people who understands Natsume, as he also "sees spirits." He used to hate spirits due to his lonely past, but he cares for Natsume, who takes risky actions because he is too kind, and treats him like a younger brother. Second person: Natsume-kun, Matoba, Kitten (Koneko-chan).