Full Name: Chad Tanner (High School Boy) He is physically strong and possesses the toughness to punch a Fiend head-on without fear. As the star quarterback (QB) of the East Side High football team, he is a well-known and highly popular figure. He reigns at the very top of the school social hierarchy. Relationship with Amber: Recognized by everyone as the "perfect, beautiful top couple" alongside Prom Queen candidate Amber. While he is an all-around athlete popular with the female students, his academic grades are not very good. He wears a traditional letterman jacket in East Side High's red and white colors. Underneath the jacket, he wears a simple gray hoodie. He wears classic blue denim jeans for ease of movement and sporty sneakers.

Full Name: Samantha (Sam) Smith (High School Girl) She has a quiet and reserved personality. She struggles to look cool, but her efforts usually backfire. She is so inconspicuous that even bullies fail to notice her existence, placing her at the absolute bottom of the social hierarchy as an "invisible" presence. Her online pen pals and her pet rabbit, Sprinkles, are her emotional support. She secretly harbors romantic feelings for Chad. She has a very distinctive, dorky look, wearing a green shirt, purple pants, orthodontic headgear (facebow), and orthopedic shoes.

Full Name: Amber Leslie Davis (High School Girl) A typical "Mean Girl"—arrogant and popular. A spotlight-seeker who can't stand not being the center of the world, she mercilessly showers both the killers and her fellow survivors with sharp sarcasm and complaints. She even directs provocations, irony, and verbal abuse at the Fiends. She wears a white T-shirt with "Princess" written boldly across the chest, topped with her favorite pink jacket. Bottoms: She wears active short pants. Despite being at school, she surprisingly wears flip-flops. She wears her trademark pink headband and a shining gold heart necklace around her neck.

Full Name: Nicholas (Nick) Miller (High School Boy) Originally very cowardly, he is quick to panic or whine in the face of the Fiends and their terrifying situation. He is a typical geek who loves machines, gadgets, comics, and games. He wears a checkered blue flannel shirt over a yellow inner shirt. His pants are baggy beige chinos (cargo pants). He wears casual sneakers focused on ease of walking. His trademark is a pair of large black-rimmed glasses. He always carries a backpack on his back filled with gadgets, repair tools, and geek merchandise.

Full Name: Troy Renard (High School Delinquent) Contrary to his cold attitude, he hides a passionate heart that never abandons a comrade in distress. Though he grumbles, he is the type to protect everyone on the front lines. He wears a vintage-style denim vest with the sleeves wildly cut off (sleeveless). Under the vest, he wears a simple black tank top. His pants are worn-out black skinny jeans with distressing (tears) at the knees. He wears sturdy-looking work boots. The tattoos on both arms are exposed, highlighting his delinquent-like wildness.

Full Name: Bill Williamson (Age 52) (Male Janitor at East Side High) A cruel and ruthless madman who has completely lost his sanity. He finds joy only in hacking survivors to pieces. Wielding a massive axe, he is the toughest and most combat-capable standard front-line attacker. He excels at one-hit-kill ambushes, suddenly jumping down from places like ceiling glass windows to drive his axe into a survivor's skull. He wears filthy janitor work clothes. His skin appears rotted (zombified), and he has a large scar over his left eye.

(Male) While he is poor at direct, face-to-face melee combat, he corners survivors with tricky long-range attacks. He spits "acid venom" from his mouth to deal continuous damage and fires "spider webs" to severely reduce (slow) a survivor's movement speed. He excels at setting the stage for other killers to finish the job by harassing survivors while they work or tripping up those trying to flee. He can hide in vents and other openings to drag in survivors passing directly underneath, dealing massive damage. Multiple large, eerie spider legs sprout and spread from his lower body and back.