Male. Pochita, the Chainsaw Devil he kept as a pet, gave Denji his heart. He transforms into Chainsaw Man by pulling the cord on his chest. Weapon Human. Public Safety Special Division 4. Denji is a character faithful to honest and simple desires. His actions, which can sometimes feel lewd, stem from a human longing caused by extreme deprivation. He is eccentric and comical. He possesses an unpredictable charm and a heart that wants to protect those precious to him.

Female. She has an inscrutable charm. Kind, intelligent, and cool-headed, but possesses a strong inner desire for dominance. A character who desires equal relationships yet ends up manipulating people in the wrong ways. A high-ranking Devil Hunter in Public Safety, reporting directly to the Chief Cabinet Secretary and commanding the hunters. She kills targets by having sacrificial people say the target's name, then uses hand gestures to crush and burst the target.

Male. Public Safety Special Division 4. A cool-headed individual who became a Devil Hunter to seek revenge against the Gun Devil, who took his family. Inwardly, he has a warm personality and deeply cares for his colleagues. He has a strong sense of responsibility and sacrifice, to the point of giving up his lifespan. He has a realistic side, being strict with Denji and Power's immaturity. He is contracted with the Fox Devil; by shouting "Kon," he summons the fox's head. Immediately after, the Fox Devil's head bites off whatever is within the field of vision formed by his fingers. In exchange, he provides parts of his body.

Female. Public Safety Special Division 4. Appears cool and strong on the outside. Due to the sadness of losing many colleagues, she is actually quite fragile. Because of this, she especially treasures Aki. She plays pranks (kisses) when drunk. She is contracted with the Ghost Devil and fights by summoning ghost hands.

Female. Public Safety Special Division 4. Whimsical and arrogant. A Blood Fiend who treasures her cat and grows by learning human affection alongside Denji. She manipulates blood at will. She creates various weapons (scythes) using her own blood.

Female. Public Safety Special Division 4. Seemingly timid and cowardly. She cries often and screams. However, she displays hidden abilities in extreme situations to overpower enemies. She is often pushed around by other colleagues. She has a surprising charm in that she gets her work done well. Weapon: Kitchen knife.